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WA researchers look at potential to use medicinal cannabis for weight loss

cannamed by cannamed
February 15, 2022
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WA researchers look at potential to use medicinal cannabis for weight loss
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To a layperson, it could appear counterintuitive {that a} plant with a popularity for giving individuals the “munchies” could be used to facilitate weight reduction.

Key factors:

  • A college has teamed up with a medicinal hashish firm to discover if the plant can be utilized to assist with weight reduction
  • Researchers say there aren’t many pharmaceutical remedies for weight problems
  • It is hoped extra analysis into the plant will assist break down the stigma surrounding medicinal hashish

However in recent times, scientific communities around the globe are focusing extra consideration towards the therapeutic advantages of hashish, together with the potential for the plant for use to deal with weight problems.

Researchers at Curtin College in Western Australia have teamed up with native medical hashish producer, Little Inexperienced Pharma, to research the potential utility of the plant as an help for weight reduction.

Lead researcher and Professor of Metabolism, Marco Falasca, stated the analysis had the potential to ship a safer various to at present accessible weight-loss medication.

“There should not many remedies for weight problems, they usually all include negative effects,” Professor Falasca stated.

“Compounds current in our physique management satiety and all of the mechanisms associated to weight problems.”

“We have to use the identical mechanisms as nature — this manner, we imagine we’ll have fewer negative effects.”

Professor Falasca acknowledged that, resulting from unfavourable preconceptions of the hashish plant, there was nonetheless some hesitation from medical doctors in prescribing medicinal hashish to sufferers.

A man looks closely at a cannabis plant
There’s hope hashish will ultimately be confirmed as a safer various to present weight-loss medication.(ABC South West: Asha Sofa)

“It is necessary to beat the issue we’ve with the stigma round cannabinoid analysis,” Professor Falasca stated.

“One of the best ways ahead is to supply scientific proof that these remedies are working — to offer scientific dignity to what we’re doing.”

Leon Warne, Head of Analysis and Innovation at Little Inexperienced Pharma, echoed these sentiments however added attitudes had been already altering.

“I believe there is definitely a rising wave of medical doctors who’re seeing … the areas the place this drug can successfully be used to enhance the standard of lifetime of many sufferers,” Dr Warne stated.

How wouldn’t it work?

A room with medicinal cannabis
It is believed the plant may unearth the pure cannabinoids within the physique and assist with weight reduction.(ABC South West: Asha Sofa)

Dr Warne defined cannabinoid perform was fairly sophisticated and human our bodies had a pure cannabinoid system, much like that present in hashish vegetation.

As an example how this works in drugs, he used the analogy of a lock and key, the place the physique’s receptors acted because the lock, while the hashish plant compound functioned as the important thing.

“When the [plant cannabinoids] have interaction with that lock, they unearth the pure cannabinoids inside the physique to have these results that we’re seeing.”

‘Extremely experimental’ analysis in early phases

Medicinal hashish has been authorized in Australia for six years however may be very strictly regulated by the Therapeutic Items Administration — one thing Dr Warne believes is an efficient factor for each sufferers and analysis.

“[Due to the] robust regulatory stance of the TGA round guaranteeing the protection, efficacy and high quality requirements of medicinal hashish merchandise, the usual of the medicines we’re producing are extraordinarily excessive,” he stated.

“While we’d suppose that locations like North America could be extra liberal with their approaches in the direction of hashish, the standard of the medication shouldn’t be on the identical requirements.”

“We now have this actually nice alternative right here in Australia to conduct high-quality analysis.”

Prof. Marco Falasca and Dr Leon Warne in front of Cannabis
Marco Falasca and Leon Warne try to interrupt down the stigma surrounding medicinal hashish.

Joe Kosterich, a Perth-based GP and medical adviser to Little Inexperienced Pharma, stated the validity of the research being carried out had been supported by different worldwide information.

“That is extremely early experimental work so it will possibly’t be prescribed on that foundation, however the analysis that is going to be undertaken in Perth builds on a few of this experimental information,” Dr Kosterich stated.

“It is actually going to look to see whether or not, out in the true world, this generally is a utilization [of the cannabis plant].”

“I do not suppose we are able to pre-empt or pre-judge … that is why you do the analysis — to search out out,” he stated.

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